How is PNH diagnosed?
Historically, the diagnosis of PNH has been known to take a long time, sometimes even months or years.
This is because the signs and symptoms of PNH occur in many diseases and PNH affects different people in different ways. PNH is also very rare and so it may not be the first disease that a doctor thinks of when they see a patient.
PNH is best diagnosed using a test called flow cytometry that looks at the structure of the blood cells. It examines individual blood cells to see if they have the normal proteins on their surface which can protect them from the immune system.
If these proteins are present the blood cell is normal, if they are not it is a PNH cell.